Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25018417 | 0.93 | FURIN (0.40) | FURINHTTSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL18431308 | 0.89 | FURIN (0.41) | FURINHTTSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL22546818 | 0.89 | SIRT2 (0.42) | FURINHTTSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL20798918 | 0.89 | SIRT2 (0.42) | FURINHTTSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL24451192 | 0.89 | SIRT2 (0.42) | FURINHTTSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL24450761 | 0.89 | SIRT2 (0.42) | FURINHTTSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL19389191 | 0.87 | SIRT2 (0.41) | FURINHTTSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL19340296 | 0.86 | FURIN (0.40) | FURINHTTSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL25490828 | 0.86 | HTT (0.41) | FURINHTTSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL18660692 | 0.86 | SIRT2 (0.43) | FURINHTTSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020210692-A1 | PROGRAMMABLE POLYMERIC DRUGS | SONY CORPORATION (JP) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020210689-A1 | PROGRAMMABLE POLYMERIC DRUGS | SONY CORPORATION (JP) | 2020-10-15 | — | — | WO | disclosed |