Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 8/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22541187 | 0.91 | BRD4 (0.44) | BRD4CACNA1GHRH3GLSMAPT | |
| SCHEMBL22541143 | 0.90 | BRD4 (0.51) | BRD4CACNA1GHRH3GLSMAPT | |
| SCHEMBL22541243 | 0.89 | BRD4 (0.43) | BRD4 | |
| SCHEMBL22541295 | 0.88 | BRD4 (0.47) | BRD4CACNA1GHRH3GLSMAPT | |
| SCHEMBL22541185 | 0.88 | BRD4 (0.41) | BRD4HRH3 | |
| SCHEMBL22541142 | 0.85 | BRD4 (0.40) | BRD4HRH3 | |
| SCHEMBL24452615 | 0.84 | HRH3 (0.41) | BRD4HRH3 | |
| SCHEMBL22541134 | 0.79 | BRD4 (0.51) | BRD4GLSMAPT | |
| SCHEMBL22541259 | 0.78 | BRD4 (0.44) | BRD4GLS | |
| SCHEMBL22541139 | 0.77 | BRD4 (0.51) | BRD4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020207396-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020207395-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO., LTD. (CN) | 2020-10-15 | — | — | WO | disclosed |