Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | RHEB | Q15382 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21853840 | 1.00 | GSK3B (0.38) | GSK3BGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL20012465 | 0.91 | GSK3B (0.39) | GSK3BGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL21899492 | 0.91 | GSK3B (0.39) | GSK3BGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL19995394 | 0.87 | KCNH2 (0.36) | GSK3BHTR2CHTR2AHTR2BIDO1 | |
| SCHEMBL21853819 | 0.87 | KCNH2 (0.36) | GSK3BHTR2CHTR2AHTR2BIDO1 | |
| SCHEMBL30060743 | 0.87 | KCNH2 (0.36) | GSK3BHTR2CHTR2AHTR2BIDO1 | |
| SCHEMBL20011900 | 0.87 | KCNH2 (0.36) | GSK3BHTR2CHTR2AHTR2BIDO1 | |
| SCHEMBL20012467 | 0.85 | GSK3B (0.51) | GSK3BGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL20011889 | 0.85 | GSK3B (0.51) | GSK3BGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL21853843 | 0.83 | GSK3B (0.38) | GSK3BGRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515903-B1 | PREPARATION AND USES OF PYRIMIDINONE DERIVATIVES | CANCER RESEARCH TECH LTD (GB) | 2020-10-21 | — | — | EP | disclosed |