SCHEMBL22551571

SCHEMBL22551571

CC(C)(C)CC(N)S(=O)(=O)O

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13570260 0.77 TP53 (0.32) TP53
SCHEMBL22551598 0.76 TP53 (0.33) TP53
SCHEMBL17540923 0.75 TP53 (0.32) TP53
SCHEMBL23781790 0.75 TP53 (0.36) TP53
SCHEMBL1537037 0.73 TP53 (0.30) TP53
SCHEMBL5170437 0.73 TP53 (0.35) TP53
SCHEMBL360350 0.73
SCHEMBL27475936 0.71 SLC22A6 (0.33)
SCHEMBL170745 0.70
SCHEMBL2742784 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110396165-B Ionically hydrophilicized polyisocyanates and antioxidants 科思创德国股份有限公司 2022-12-06 CN disclosed
CN-112041369-B Ionically hydrophilicized polyisocyanates, water content 科思创知识产权两合公司 2022-11-29 CN disclosed
CN-115066445-A Polyisocyanate formulations 科思创德国股份有限公司 2022-09-16 CN disclosed
CN-113651944-B Ionically hydrophilicized polyisocyanates having improved drying properties 科思创知识产权两合公司 2022-07-15 CN disclosed
CN-112062935-B Preparation method and application of odorless water-dispersible polyisocyanate 广东也乐新材料制造有限公司 2022-02-11 CN disclosed
CN-112566957-B Ionically hydrophilicized polyisocyanates having improved drying properties 科思创知识产权两合公司 2021-12-10 CN disclosed
CN-113651944-A Ionically hydrophilicized polyisocyanates having improved drying properties 科思创知识产权两合公司 2021-11-16 CN disclosed
EP-3875513-A1 IONICALLY HYDROPHILIZED POLYISOCYANATES AND RADICAL SCAVENGER AND/OR PEROXIDE DECOMPOSITION AGENT Covestro Intellectual Property GmbH & Co. KG (DE) 2021-09-08 EP disclosed
CN-112566957-A Ionically hydrophilicized polyisocyanates having improved drying properties 科思创知识产权两合公司 2021-03-26 CN disclosed
CN-112062935-A Preparation method and application of odorless water-dispersible polyisocyanate 广东也乐新材料制造有限公司 2020-12-11 CN disclosed
CN-112041369-A Ionically hydrophilicized polyisocyanates, water content 科思创知识产权两合公司 2020-12-04 CN disclosed
EP-3724251-A1 IONIC HYDROPHILIZED POLYISOCYANATES, WATER CONTENT Covestro Intellectual Property GmbH & Co. KG (DE) 2020-10-21 EP disclosed
CN-110396165-A Ionic hydrophilic polyisocyanates and antioxidant COVESTRO DEUTSCHLAND AG 2019-11-01 CN disclosed
CN-110396173-A Ionic hydrophilic polyisocyanates and free radical scavenger and/or peroxide decomposer COVESTRO DEUTSCHLAND AG 2019-11-01 CN disclosed
CN-1839118-B Methods and compositions for treating amyloid-related diseases BELLUS HEALTH INTERNATIONAL LTD 2010-06-16 CN disclosed
CN-101712640-A methods and compositions for treating amyloid-related diseases BELLUS HEALTH INTERNAT LT 2010-05-26 CN disclosed
CN-1839118-A Methods and compositions for treating amyloid-related diseases NEUROCHEM INTERNAT LTD (CH) 2006-09-27 CN disclosed