Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249849 | 0.96 | EGFR (0.76) | EGFRERBB2 | |
| SCHEMBL2252459 | 0.96 | EGFR (0.84) | EGFRERBB2 | |
| SCHEMBL2250506 | 0.95 | EGFR (0.77) | EGFRERBB2 | |
| SCHEMBL2251476 | 0.91 | EGFR (0.71) | EGFRERBB2 | |
| SCHEMBL15163351 | 0.90 | EGFR (0.81) | EGFRERBB2 | |
| SCHEMBL15163349 | 0.89 | EGFR (0.83) | EGFRERBB2 | |
| SCHEMBL17940084 | 0.89 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL2249784 | 0.88 | EGFR (0.75) | EGFRERBB2 | |
| SCHEMBL3419722 | 0.87 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL16606118 | 0.87 | EGFR (0.87) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003658-B2 | Quinazoline derivatives for inhibiting cancer cell growth and method for the preparation thereof | HANMI HOLDINGS CO., LTD. (KR) | 2011-08-23 | — | — | US | claimed |
| US-8003658-B2 | Quinazoline derivatives for inhibiting cancer cell growth and method for the preparation thereof | HANMI HOLDINGS CO., LTD. (KR) | 2011-08-23 | — | — | US | disclosed |