Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22571361 | 0.88 | RXFP1 (0.41) | RXFP1MTORTAS2R14MAPK8AKR1C3 | |
| SCHEMBL22556362 | 0.86 | RXFP1 (0.46) | RXFP1TAS2R14MAPK8THRBMT-CO2 | |
| SCHEMBL23701615 | 0.84 | RXFP1 (0.46) | RXFP1MTORTAS2R14MAPK8AKR1C3 | |
| SCHEMBL23701543 | 0.83 | RXFP1 (0.48) | RXFP1MTORTAS2R14MAPK8AKR1C3 | |
| SCHEMBL23701523 | 0.81 | RXFP1 (0.47) | RXFP1MTORTAS2R14MAPK8AKR1C3 | |
| SCHEMBL23701621 | 0.80 | RXFP1 (0.46) | RXFP1MTORTAS2R14MAPK8AKR1C3 | |
| SCHEMBL22556328 | 0.80 | RXFP1 (0.46) | RXFP1MTORTAS2R14MAPK8AKR1C3 | |
| SCHEMBL22556300 | 0.80 | RXFP1 (0.49) | RXFP1TAS2R14MAPK8AKR1C3AKR1C2 | |
| SCHEMBL23701619 | 0.79 | RXFP1 (0.45) | RXFP1MTORTAS2R14MAPK8AKR1C3 | |
| SCHEMBL22556343 | 0.79 | RXFP1 (0.48) | RXFP1TAS2R14MAPK8AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793551-A1 | OXADIAZOLE COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2021-03-24 | — | — | EP | disclosed |
| WO-2019222431-A9 | OXADIAZOLE COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2020-10-22 | — | — | WO | disclosed |