Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | BUB1 | O43683 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463745 | 1.00 | MEN1 (0.55) | MEN1KMT2ANPC1RXFP1LMNA | |
| SCHEMBL23701612 | 0.87 | RXFP1 (0.50) | MEN1KMT2ARXFP1TRPV1 | |
| SCHEMBL23713166 | 0.86 | MEN1 (0.49) | MEN1KMT2ANPC1RXFP1LMNA | |
| SCHEMBL30463796 | 0.82 | KMT2A (0.51) | KMT2ARXFP1MAPTJAK2 | |
| SCHEMBL17064024 | 0.80 | MEN1 (0.55) | MEN1KMT2ANPC1LMNANPSR1 | |
| SCHEMBL17064026 | 0.80 | MEN1 (0.55) | MEN1KMT2ANPC1LMNANPSR1 | |
| SCHEMBL4954647 | 0.79 | NPC1 (0.59) | MEN1KMT2ANPC1LMNANPSR1 | |
| SCHEMBL4954654 | 0.79 | NPC1 (0.59) | MEN1KMT2ANPC1LMNANPSR1 | |
| SCHEMBL15244601 | 0.77 | NPC1 (0.53) | MEN1KMT2ANPC1LMNANPSR1 | |
| SCHEMBL29888333 | 0.76 | RXFP1 (0.48) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793551-A1 | OXADIAZOLE COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2021-03-24 | — | — | EP | disclosed |
| WO-2019222431-A9 | OXADIAZOLE COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2020-10-22 | — | — | WO | disclosed |
| WO-2019222431-A9 | OXADIAZOLE COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2020-10-22 | — | — | WO | disclosed |