Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22565438 | 1.00 | AR (0.58) | ARPGR | |
| Hydrochloric Acid SCHEMBL26113781 | 0.99 | AR (0.57) | ARPGR | |
| Hydrochloric Acid SCHEMBL26113776 | 0.99 | AR (0.57) | ARPGR | |
| SCHEMBL26932967 | 0.88 | AR (0.56) | ARPGR | |
| SCHEMBL26932970 | 0.88 | AR (0.56) | ARPGR | |
| SCHEMBL3197384 | 0.87 | AR (0.66) | ARPGR | |
| SCHEMBL3200817 | 0.87 | AR (0.70) | ARPGR | |
| SCHEMBL2119294 | 0.86 | AR (0.58) | AR | |
| SCHEMBL22565516 | 0.86 | AR (0.58) | ARPGR | |
| SCHEMBL2617743 | 0.86 | AR (0.58) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020211822-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | 成都海创药业有限公司 | 2020-10-22 | — | — | WO | disclosed |