Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23477961 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C19CYP2D6MAPTHDAC8 | |
| SCHEMBL29074198 | 0.91 | GRM2 (0.40) | CYP3A4CYP2C19CYP2D6MAPTCTSD | |
| SCHEMBL20072321 | 0.91 | GRM2 (0.40) | CYP3A4CYP2C19CYP2D6MAPTCTSD | |
| SCHEMBL598381 | 0.91 | GRM2 (0.40) | CYP3A4CYP2C19CYP2D6MAPTCTSD | |
| SCHEMBL28412417 | 0.91 | GRM2 (0.40) | CYP3A4CYP2C19CYP2D6MAPTCTSD | |
| SCHEMBL4440151 | 0.91 | GRM2 (0.40) | CYP3A4CYP2C19CYP2D6MAPTCTSD | |
| SCHEMBL1908538 | 0.91 | GRM2 (0.40) | CYP3A4CYP2C19CYP2D6MAPTCTSD | |
| SCHEMBL598403 | 0.91 | GRM2 (0.40) | CYP3A4CYP2C19CYP2D6MAPTCTSD | |
| SCHEMBL10847469 | 0.83 | GAA (0.48) | — | |
| SCHEMBL8283063 | 0.83 | GAA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10808059-B2 | Polymer | CANON KABUSHIKI KAISHA (JP) | 2020-10-20 | — | — | US | disclosed |