Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27887847 | 0.93 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL25865339 | 0.91 | TSHR (0.64) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL19934884 | 0.89 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| 2-Ethylhexanoic Acid SCHEMBL27664726 | 0.85 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL8815479 | 0.85 | GRIK1 (0.53) | TSHRHCAR2CA2MAPK1GRIK1 | |
| SCHEMBL8665338 | 0.84 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL23581478 | 0.81 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL21694364 | 0.81 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL21694377 | 0.81 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL31448297 | 0.81 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795399-B2 | UV curable adhesion promoters based on functionalised polyvinyl alcohols | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-11795399-B2 | UV curable adhesion promoters based on functionalised polyvinyl alcohols | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| EP-3507343-B1 | UV CURABLE ADHESION PROMOTERS BASED ON FUNCTIONALISED POLYVINYL ALCOHOLS | MERCK PATENT GMBH (DE) | 2020-10-21 | — | — | EP | disclosed |