Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 3/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561300 | 0.85 | TSHR (0.49) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL19934808 | 0.85 | TSHR (0.49) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL12586033 | 0.79 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28349127 | 0.74 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8064983 | 0.73 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13563722 | 0.73 | CACNA2D1 (0.36) | TSHRHSD17B10PRKCAPRKCE | |
| SCHEMBL22561244 | 0.71 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL24282492 | 0.71 | TSHR (0.67) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2608225 | 0.71 | TSHR (0.67) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL1259928 | 0.71 | TSHR (0.67) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507343-B1 | UV CURABLE ADHESION PROMOTERS BASED ON FUNCTIONALISED POLYVINYL ALCOHOLS | MERCK PATENT GMBH (DE) | 2020-10-21 | — | — | EP | disclosed |