Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148731 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2MEN1 | |
| SCHEMBL17727837 | 0.86 | MEN1 (0.42) | CHRM2CHRM1CHRM3NR1H2MEN1 | |
| SCHEMBL16245964 | 0.86 | MEN1 (0.42) | CHRM2CHRM1CHRM3NR1H2MEN1 | |
| SCHEMBL12404085 | 0.82 | NR1H2 (0.44) | CHRM2CHRM1CHRM3NR1H2MEN1 | |
| SCHEMBL25336792 | 0.81 | CHRM2 (0.44) | CHRM2CHRM1CHRM3NR1H2MEN1 | |
| SCHEMBL19369131 | 0.79 | NR1H2 (0.42) | CHRM2CHRM1CHRM3NR1H2MEN1 | |
| SCHEMBL3461197 | 0.79 | NR1H2 (0.42) | CHRM2CHRM1CHRM3NR1H2MEN1 | |
| SCHEMBL22118120 | 0.78 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2MEN1 | |
| SCHEMBL22128867 | 0.78 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2MEN1 | |
| SCHEMBL22128869 | 0.78 | CHRM2 (0.41) | CHRM2CHRM1CHRM3NR1H2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725314-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |