Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CPT2 | P23786 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BHMT | Q93088 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5856633 | 0.90 | KDM4E (0.58) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL11981948 | 0.90 | KDM4E (0.39) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL557257 | 0.87 | KDM4E (0.59) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL12808778 | 0.85 | KDM4E (0.56) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL12130380 | 0.81 | KDM4E (0.33) | KDM4E | |
| SCHEMBL14314268 | 0.81 | KDM4E (0.74) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL7083891 | 0.80 | KDM4E (0.36) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL20902791 | 0.79 | KDM4E (0.37) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL22662448 | 0.79 | KDM4E (0.52) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL16280996 | 0.79 | KDM4E (0.42) | KDM4EFFAR1CPT2TDP1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725771-A1 | ALK PROTEIN DEGRADATION AGENT AND ANTI-TUMOR APPLICATION THEREOF | Shanghaitech University (CN) | 2020-10-21 | — | — | EP | disclosed |