Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22562048 | 0.73 | BRAF (0.42) | RAF1BRAF | |
| SCHEMBL29878210 | 0.72 | RAF1 (0.58) | RAF1BRAF | |
| SCHEMBL19327940 | 0.69 | RAF1 (0.68) | RAF1BRAF | |
| SCHEMBL29877986 | 0.68 | RAF1 (0.54) | RAF1BRAF | |
| SCHEMBL26003063 | 0.68 | BRAF (0.48) | RAF1BRAF | |
| SCHEMBL25701473 | 0.67 | RAF1 (0.56) | RAF1BRAF | |
| SCHEMBL16102905 | 0.67 | RAF1 (1.00) | RAF1BRAF | |
| SCHEMBL22562118 | 0.65 | BRAF (0.34) | RAF1BRAF | |
| SCHEMBL22561940 | 0.65 | RAF1 (0.63) | RAF1BRAF | |
| SCHEMBL19328022 | 0.64 | RAF1 (0.68) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191467-B1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2020-10-21 | — | — | EP | disclosed |