Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19327983 | 0.93 | RAF1 (0.57) | RAF1BRAF | |
| SCHEMBL19327933 | 0.84 | RAF1 (0.54) | RAF1BRAF | |
| SCHEMBL22562030 | 0.83 | RAF1 (0.50) | RAF1BRAF | |
| SCHEMBL22562051 | 0.79 | RAF1 (0.56) | RAF1BRAF | |
| SCHEMBL17591668 | 0.78 | RAF1 (0.67) | RAF1BRAF | |
| SCHEMBL19343153 | 0.78 | RAF1 (0.62) | RAF1BRAF | |
| SCHEMBL17591638 | 0.77 | RAF1 (0.75) | RAF1BRAF | |
| SCHEMBL19327946 | 0.77 | RAF1 (0.68) | RAF1BRAF | |
| SCHEMBL19328035 | 0.77 | RAF1 (0.61) | RAF1BRAF | |
| SCHEMBL19328127 | 0.76 | RAF1 (0.60) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191467-B1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2020-10-21 | — | — | EP | disclosed |