Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.51 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21835861 | 0.91 | ELANE (0.49) | ELANECCR1MEN1KMT2AAVPR1B | |
| SCHEMBL21835860 | 0.91 | ELANE (0.49) | ELANECCR1MEN1KMT2AAVPR1B | |
| SCHEMBL19502934 | 0.90 | ELANE (0.49) | ELANECCR1MEN1KMT2AAVPR1B | |
| SCHEMBL21860387 | 0.89 | ELANE (0.49) | ELANECCR1MEN1KMT2AAVPR1B | |
| SCHEMBL19523399 | 0.88 | ELANE (0.51) | ELANECCR1MEN1KMT2AAVPR1B | |
| SCHEMBL28663217 | 0.86 | ELANE (0.45) | ELANECCR1MEN1KMT2AAVPR1B | |
| SCHEMBL19523397 | 0.86 | ELANE (0.48) | ELANECCR1MEN1KMT2AAVPR1B | |
| SCHEMBL19523396 | 0.86 | ELANE (0.48) | ELANECCR1MEN1KMT2AAVPR1B | |
| SCHEMBL19502916 | 0.86 | ELANE (0.45) | ELANECCR1MEN1KMT2AAVPR1B | |
| SCHEMBL19502918 | 0.86 | ELANE (0.45) | ELANECCR1MEN1KMT2AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464273-B9 | IMIDAZOLONE COMPOUNDS AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | CHIESI FARM SPA (IT) | 2020-10-21 | — | — | EP | disclosed |