Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472114 | 0.83 | RARB (0.50) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL959756 | 0.83 | RARB (0.53) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL15987949 | 0.82 | TP53 (0.53) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL20178570 | 0.82 | TP53 (0.53) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL28262824 | 0.82 | TP53 (0.53) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL23168986 | 0.81 | RARB (0.51) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL2231026 | 0.81 | TP53 (0.56) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL11590735 | 0.81 | TP53 (0.56) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL9812197 | 0.81 | TP53 (0.51) | RARBTP53TSHRPLA2G4BMEN1 | |
| Hydrochloric Acid SCHEMBL10528458 | 0.81 | TP53 (0.51) | RARBTP53TSHRPLA2G4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725777-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2020-10-21 | — | — | EP | disclosed |