⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31172546 | 0.69 | — | — | |
| SCHEMBL16114785 | 0.66 | — | — | |
| SCHEMBL13280909 | 0.60 | — | — | |
| SCHEMBL5028277 | 0.60 | — | — | |
| SCHEMBL22015774 | 0.59 | — | — | |
| SCHEMBL22562982 | 0.55 | — | — | |
| SCHEMBL2438093 | 0.54 | — | — | |
| SCHEMBL24373234 | 0.51 | — | — | |
| SCHEMBL3628766 | 0.51 | — | — | |
| Propiolactone SCHEMBL10680620 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020212530-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2020-10-22 | — | — | WO | disclosed |
| EP-3725777-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2020-10-21 | — | — | EP | disclosed |