SCHEMBL22562986

SCHEMBL22562986

Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)cc(-n3c4ccccc4c4cc(-c5ccc(C)cc5C)ccc43)c2-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 3/20 0.36
ABCG2 Q9UNQ0 8/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C19 P33261 2/20 0.34
CLK4 Q9HAZ1 2/20 0.34
NPY5R Q15761 2/20 0.34
LMNA P02545 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ABCB1 P08183 3/20 0.33
PDE9A O76083 1/20 0.32
PDE1C Q14123 1/20 0.32
METAP2 P50579 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21109679 0.97 ABCG2 (0.36) PTGER4ABCG2MEN1KMT2AALDH1A1
SCHEMBL21108766 0.94 ABCG2 (0.34) ABCG2MEN1KMT2AALDH1A1CYP1A2
SCHEMBL22563367 0.94 ADORA2A (0.37) PTGER4ABCG2MEN1KMT2AALDH1A1
SCHEMBL21278807 0.92 HPGD (0.36) PTGER4ABCG2MEN1KMT2AALDH1A1
SCHEMBL22562985 0.91 PTGER4 (0.38) PTGER4ABCG2MEN1KMT2AALDH1A1
SCHEMBL20114558 0.91 PTGER4 (0.38) PTGER4ABCG2MEN1KMT2AALDH1A1
SCHEMBL22563578 0.90 KDM4E (0.39) ABCG2MEN1KMT2AALDH1A1LMNA
SCHEMBL19943118 0.90 PTGER4 (0.38) PTGER4ABCG2MEN1KMT2AALDH1A1
SCHEMBL22563095 0.90 ABCG2 (0.39) PTGER4ABCG2MEN1KMT2AALDH1A1
SCHEMBL22242928 0.90 PTGER4 (0.38) PTGER4ABCG2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507285-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed