Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19933547 | 0.90 | TRPV1 (0.63) | TRPV1KCNK3KCNK9MCHR1PTPN2 | |
| SCHEMBL18573396 | 0.83 | TRPV1 (0.71) | TRPV1KCNK3KCNK9MCHR1PTPN2 | |
| SCHEMBL14082212 | 0.80 | NPC1 (0.68) | TRPV1KCNK3KCNK9 | |
| SCHEMBL14313610 | 0.79 | TRPV1 (0.72) | TRPV1PTPN2PTPN1ADORA3 | |
| SCHEMBL19933630 | 0.78 | TRPV1 (0.63) | TRPV1PTPN2PTPN1 | |
| SCHEMBL14082180 | 0.76 | TRPV1 (0.75) | TRPV1KCNK3KCNK9MCHR1PTPN2 | |
| SCHEMBL14082276 | 0.76 | TRPV1 (0.60) | TRPV1KCNK3KCNK9MCHR1PTPN2 | |
| SCHEMBL14082185 | 0.76 | TRPV1 (0.71) | TRPV1ADORA3 | |
| SCHEMBL14082286 | 0.74 | TRPV1 (0.65) | TRPV1MCHR1PTPN2PTPN1 | |
| SCHEMBL14082220 | 0.74 | NPC1 (0.61) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515925-B1 | BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-10-21 | — | — | EP | disclosed |