SCHEMBL22563560

SCHEMBL22563560

Cc1cc(C)cc(-c2ccc3c4ccc(-c5cc(C)cc(C)c5)cc4n(-c4cc(C#N)cc(-n5c6cc(-c7cc(C)cc(C)c7)ccc6c6ccc(-c7cc(C)cc(C)c7)cc65)c4-c4nc(C)cc(C)n4)c3c2)c1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 1/20 0.36
CHEK1 O14757 1/20 0.35
KDM5B Q9UGL1 1/20 0.35
HSD11B1 P28845 1/20 0.34
GRM5 P41594 1/20 0.34
ABCG2 Q9UNQ0 2/20 0.33
KCNH2 Q12809 1/20 0.33
SCN10A Q9Y5Y9 1/20 0.33
EGLN2 Q96KS0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23487620 0.95 ABCG2 (0.35) IRAK4CHEK1KDM5BHSD11B1GRM5
SCHEMBL22563588 0.93 CHEK1 (0.36) IRAK4CHEK1ABCG2
SCHEMBL23487587 0.92 CHEK1 (0.38) IRAK4CHEK1HSD11B1ABCG2
SCHEMBL22563564 0.92 CHEK1 (0.41) IRAK4CHEK1HSD11B1ABCG2
SCHEMBL23487779 0.91 ABCG2 (0.38) IRAK4CHEK1KDM5BGRM5ABCG2
SCHEMBL19943112 0.91 CHEK1 (0.35) IRAK4CHEK1KDM5BGRM5KCNH2
SCHEMBL22563478 0.90 CHEK1 (0.34) IRAK4CHEK1HSD11B1ABCG2KCNH2
SCHEMBL19909413 0.89 IRAK4 (0.37) IRAK4CHEK1KDM5BHSD11B1GRM5
SCHEMBL22563570 0.88 ABCG2 (0.43) IRAK4CHEK1GRM5ABCG2
SCHEMBL22563587 0.88 ABCG2 (0.36) IRAK4CHEK1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-10 US disclosed
EP-3580300-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, OR51E2, OCIAD2 IRAK4 1613/4885CHEK1 2408/4885KDM5B 4508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.