SCHEMBL22563659

SCHEMBL22563659

CCCC1(C)OC(C)CN1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EBP Q15125 1/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18124961 0.69
SCHEMBL679663 0.69
SCHEMBL18124968 0.69
SCHEMBL3255961 0.67 EBP (0.31) EBPSIGMAR1
SCHEMBL9806547 0.66 EBP (0.46) EBPSIGMAR1
SCHEMBL20438505 0.63
SCHEMBL18780536 0.63
SCHEMBL10694741 0.62 EBP (0.38) EBPSIGMAR1
SCHEMBL11165849 0.61
SCHEMBL25921542 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3466490-B1 POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES INC (US) 2020-10-21 EP disclosed