Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12547102 | 0.69 | CARM1 (0.40) | CARM1PRMT6PRMT8 | |
| SCHEMBL11122374 | 0.66 | — | — | |
| SCHEMBL18124965 | 0.65 | — | — | |
| SCHEMBL19977336 | 0.63 | — | — | |
| SCHEMBL14467775 | 0.62 | — | — | |
| SCHEMBL22123732 | 0.62 | CARM1 (0.45) | CARM1PRMT6PRMT8 | |
| SCHEMBL23330704 | 0.59 | CARM1 (0.37) | CARM1PRMT6PRMT8 | |
| SCHEMBL20226979 | 0.59 | — | — | |
| SCHEMBL19217076 | 0.58 | KMT2A (0.32) | — | |
| SCHEMBL19993069 | 0.57 | CARM1 (0.65) | CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466490-B1 | POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES INC (US) | 2020-10-21 | — | — | EP | disclosed |