Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.72 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | TNKS | O95271 | 2/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.52 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22566109 | 1.00 | AR (0.72) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22557880 | 0.91 | AR (0.66) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22557879 | 0.91 | AR (0.66) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22564952 | 0.90 | AR (0.73) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22565013 | 0.90 | AR (0.79) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22565749 | 0.90 | AR (0.79) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22557804 | 0.89 | AR (0.64) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL20046577 | 0.89 | AR (0.64) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22557805 | 0.89 | AR (0.64) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL30349579 | 0.89 | AR (0.64) | ARPGRTNKSPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |
| WO-2020211822-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | 成都海创药业有限公司 | 2020-10-22 | — | — | WO | disclosed |