Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 0.76 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22873319 | 0.91 | AR (0.74) | AR | |
| SCHEMBL17519967 | 0.91 | AR (0.74) | AR | |
| SCHEMBL17519973 | 0.89 | AR (0.71) | AR | |
| SCHEMBL22565142 | 0.89 | AR (0.68) | AR | |
| SCHEMBL17517171 | 0.88 | AR (0.70) | AR | |
| SCHEMBL27027588 | 0.88 | AR (0.70) | AR | |
| SCHEMBL22565156 | 0.87 | AR (0.71) | AR | |
| SCHEMBL17517175 | 0.87 | AR (0.68) | AR | |
| SCHEMBL22566107 | 0.86 | AR (0.73) | AR | |
| SCHEMBL22565151 | 0.85 | AR (0.69) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |
| WO-2020211822-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | 成都海创药业有限公司 | 2020-10-22 | — | — | WO | disclosed |