Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22565196 | 0.89 | AR (0.38) | ARABCC9 | |
| SCHEMBL22565201 | 0.86 | AR (0.37) | AR | |
| SCHEMBL22565229 | 0.84 | — | — | |
| SCHEMBL22565200 | 0.83 | NPC1 (0.35) | — | |
| SCHEMBL22565339 | 0.80 | AR (0.49) | AR | |
| SCHEMBL22565504 | 0.78 | AR (0.39) | AR | |
| SCHEMBL22565335 | 0.78 | AR (0.49) | AR | |
| SCHEMBL22565205 | 0.75 | AR (0.39) | AR | |
| SCHEMBL22565338 | 0.73 | MAPT (0.35) | AR | |
| SCHEMBL22565333 | 0.71 | AR (0.32) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020211822-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | 成都海创药业有限公司 | 2020-10-22 | — | — | WO | disclosed |