SCHEMBL225684

SCHEMBL225684

COC(C)(C)CC(C)C#N

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL21625742 0.95 TSHR (0.35) TSHRALDH1A1TDP1
SCHEMBL8410232 0.80
SCHEMBL10629039 0.79 TSHR (0.33) TSHR
SCHEMBL665307 0.76
SCHEMBL1659729 0.74 TSHR (0.30) TSHR
SCHEMBL10629093 0.73 TSHR (0.32) TSHR
SCHEMBL11710632 0.72
SCHEMBL17935616 0.72 TSHR (0.39) TSHR
SCHEMBL15309715 0.72 TSHR (0.39) TSHR
SCHEMBL14041050 0.72 TSHR (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3004 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353838-A1 METHOD FOR PREPARING 4'-THIO-5-AZA-2'-DEOXYCYTIDINE PINOTBIO, INC. (KR) 2025-11-20 US claimed
US-20250161466-A1 CONJUGATES OF PHENYLALANINE AMMONIA-LYASE AND POEGMA AND METHODS FOR THEIR USE BIOMARIN PHARMACEUTICAL INC. (US) 2025-05-22 US claimed
EP-4524145-A1 METHOD FOR PREPARING 4?-THIO-5-AZA-2?-DEOXYCYTIDINE Pinotbio, Inc. (KR) 2025-03-19 EP claimed
US-20240279142-A1 METHOD FOR PRODUCING CYCLOALKYL BROMIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-08-22 US claimed
EP-3523335-B2 VINYLIDENE FLUORIDE AND TRIFLUOROETHYLENE CONTAINING POLYMERS LATEXES SOLVAY SPECIALTY POLYMERS IT (IT) 2024-05-15 EP claimed
CN-117820524-A Polyvinylidene fluoride resin, preparation method and application thereof 万华化学集团股份有限公司 2024-04-05 CN claimed
CN-117813549-A Curable resin composition 因美纳有限公司 2024-04-02 CN claimed
CN-117038150-B UV curing conductive silver paste with good adhesion to aluminum foil and preparation method thereof 深圳市通泰盈科技股份有限公司 2024-02-02 CN claimed
CN-115043963-B Polyvinylidene fluoride dispersion liquid with high solid content and preparation method and application thereof 万华化学(四川)电池材料科技有限公司 2023-12-19 CN claimed
WO-2023239190-A1 METHOD FOR PREPARING 4'-THIO-5-AZA-2'-DEOXYCYTIDINE 주식회사 피노바이오 2023-12-14 WO claimed
US-5916981-A PRESSURE SENSITIVE ADHESIVES OF POLYSILOXANES AND CATALYSTS DOW CORNING CORPORATION (US) 1999-06-29 US claimed
WO-1999020659-A1 END-FUNCTIONALIZED POLYMERS BY CONTROLLED FREE-RADICAL POLYMERIZATION PROCESS AND POLYMERS MADE THEREFROM THE B.F. GOODRICH COMPANY (US) 1999-04-29 WO claimed
EP-0867492-A2 Silicone pressure sensitive adhesive compositions DOW CORNING CORPORATION (US) 1998-09-30 EP claimed
EP-0867493-A2 Silicone pressure sensitive adhesive compositions DOW CORNING CORPORATION (US) 1998-09-30 EP claimed
EP-0856011-A2 HETEROGENEOUS POLYMERIZATIONS IN CARBON DIOXIDE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1998-08-05 EP claimed
US-5776614-A Silicone pressure sensitive adhesive compositions DOW CORNING CORPORATION (US) 1998-07-07 US claimed
WO-1997014720-A2 HETEROGENEOUS POLYMERIZATIONS IN CARBON DIOXIDE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1997-04-24 WO claimed
EP-0239035-A2 Process for preparing fine particles of cured polymers, and their use BASF Aktiengesellschaft (DE) 1987-09-30 EP claimed
US-4485225-A USING RADICAL INITIATOR; GELATION INHIBITION KURARAY CO., LTD. (JP) 1984-11-27 US claimed
US-4232141-A ADDING AN AQUEOUS DISPERSION OF POWDERED INITIATOR; EMULSION POLYMERIZATION SHIN-ETSU CHEMICAL CO., LTD. (JP) 1980-11-04 US claimed