Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508980 | 0.76 | KMT2A (0.48) | CPN1CPB2KMT2ASMN1; SMN2CHEK1 | |
| SCHEMBL22588871 | 0.63 | KDM4E (0.34) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL16475935 | 0.61 | CPN1 (0.47) | CPN1CPB2KMT2AKDM4EMAPT | |
| SCHEMBL25662162 | 0.60 | CPN1 (0.57) | CPN1CPB2KMT2AKDM4EMAPT | |
| SCHEMBL25662154 | 0.60 | CPN1 (0.57) | CPN1CPB2KMT2AKDM4EMAPT | |
| SCHEMBL2262751 | 0.60 | CPN1 (0.57) | CPN1CPB2KMT2AKDM4EMAPT | |
| SCHEMBL2262755 | 0.60 | CPN1 (0.57) | CPN1CPB2KMT2AKDM4EMAPT | |
| SCHEMBL1527404 | 0.60 | CPN1 (0.57) | CPN1CPB2KMT2AKDM4EMAPT | |
| SCHEMBL25660410 | 0.60 | CPN1 (0.57) | CPN1CPB2KMT2AKDM4EMAPT | |
| SCHEMBL22588874 | 0.60 | RPLP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216766-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | EVOTEC INTERNATIONAL GMBH (DE) | 2020-10-29 | — | — | WO | disclosed |