Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22596082 | 0.92 | EGFR (0.76) | EGFR | |
| SCHEMBL22596185 | 0.91 | EGFR (0.80) | EGFR | |
| SCHEMBL22596081 | 0.90 | EGFR (0.72) | EGFR | |
| SCHEMBL22595158 | 0.87 | EGFR (0.70) | EGFR | |
| SCHEMBL26906791 | 0.86 | EGFR (0.84) | EGFR | |
| SCHEMBL30381642 | 0.86 | EGFR (1.00) | EGFR | |
| SCHEMBL22025688 | 0.86 | EGFR (1.00) | EGFR | |
| Trifluoroacetic Acid SCHEMBL22587624 | 0.86 | EGFR (0.72) | EGFR | |
| SCHEMBL22595203 | 0.85 | EGFR (0.82) | EGFR | |
| SCHEMBL22596146 | 0.84 | EGFR (0.77) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216371-A1 | EGFR INHIBITOR AND APPLICATION THEREOF | 江苏先声药业有限公司 | 2020-10-29 | — | — | WO | disclosed |