Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.75 |
| ▸ | INSR | P06213 | 2/20 | 0.56 |
| ▸ | IGF1R | P08069 | 2/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22595281 | 0.97 | EGFR (0.76) | EGFRINSRIGF1RALK | |
| Trifluoroacetic Acid SCHEMBL28592932 | 0.95 | EGFR (0.68) | EGFRINSRIGF1RALK | |
| SCHEMBL22595968 | 0.94 | EGFR (0.66) | EGFRINSRIGF1RALK | |
| SCHEMBL26961591 | 0.94 | EGFR (0.66) | EGFR | |
| SCHEMBL22595187 | 0.94 | EGFR (0.72) | EGFR | |
| SCHEMBL22595477 | 0.92 | EGFR (0.67) | EGFRINSRIGF1RALK | |
| SCHEMBL22595130 | 0.92 | EGFR (0.74) | EGFRINSRIGF1RALK | |
| SCHEMBL22595514 | 0.92 | EGFR (0.87) | EGFR | |
| SCHEMBL22595149 | 0.89 | EGFR (0.66) | EGFR | |
| SCHEMBL26961529 | 0.89 | EGFR (0.60) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216371-A1 | EGFR INHIBITOR AND APPLICATION THEREOF | 江苏先声药业有限公司 | 2020-10-29 | — | — | WO | disclosed |