Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22600406 | 0.80 | TSHR (0.31) | TSHR | |
| SCHEMBL24578200 | 0.69 | — | — | |
| SCHEMBL22600133 | 0.67 | CYP2A6 (0.32) | — | |
| SCHEMBL18862665 | 0.67 | TSHR (0.31) | TSHR | |
| SCHEMBL1703286 | 0.64 | — | — | |
| SCHEMBL21393343 | 0.64 | — | — | |
| SCHEMBL21227585 | 0.63 | TDP1 (0.36) | TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL23483437 | 0.62 | TSHR (0.57) | TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL17754596 | 0.59 | PDPK1 (0.38) | TSHR | |
| SCHEMBL27239649 | 0.59 | HCAR2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020219168-A1 | SMALL MOLECULE BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE, LLC (US) | 2020-10-29 | — | — | WO | disclosed |