⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3153384 | 1.00 | — | — | |
| SCHEMBL30823593 | 0.90 | FFAR3 (0.48) | — | |
| SCHEMBL9394662 | 0.90 | FFAR3 (0.48) | — | |
| SCHEMBL9394668 | 0.90 | FFAR3 (0.48) | — | |
| SCHEMBL6845294 | 0.80 | FFAR3 (0.50) | — | |
| SCHEMBL13901713 | 0.79 | FFAR3 (0.48) | — | |
| SCHEMBL13408381 | 0.79 | FFAR3 (0.48) | — | |
| SCHEMBL9393742 | 0.79 | FFAR3 (0.38) | — | |
| SCHEMBL25192322 | 0.78 | — | — | |
| SCHEMBL17210453 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192879-B2 | Chemokine receptor modulators and uses thereof | RAPT THERAPEUTICS, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200339539-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | FLX BIO, INC. | 2020-10-29 | — | — | US | disclosed |