SCHEMBL226012

SCHEMBL226012

C/C(=C\CCN=C=O)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CD81 P60033 2/20 0.35
PPARG P37231 1/20 0.31
BACE1 P56817 1/20 0.30
CPB1 P15086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15428 1.00 CD81 (0.35) CD81PPARGBACE1CPB1
Methacrylic Acid SCHEMBL22150180 0.93 CD81 (0.32) CD81
SCHEMBL2315769 0.89 CD81 (0.33) CD81PPARG
SCHEMBL33515 0.89 CD81 (0.33) CD81PPARG
SCHEMBL2316634 0.87 EP300 (0.35) CD81
SCHEMBL451025 0.87 EP300 (0.35) CD81
SCHEMBL445919 0.85 EP300 (0.38) CD81
SCHEMBL448595 0.85 EP300 (0.38) CD81
SCHEMBL9509477 0.85 EP300 (0.38) CD81
SCHEMBL448244 0.85 EP300 (0.38) CD81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 878 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3720894-B1 AMINE BASED POLYMER POLYOL STABILIZERS COVESTRO LLC (US) 2025-02-26 EP claimed
EP-4357313-A1 METHACRYLATES FORMED FROM SUGAR DERIVATIVES AS REACTIVE COMPONENTS IN REACTIVE RESINS FOR CHEMICAL FIXING Hilti Aktiengesellschaft (LI) 2024-04-24 EP claimed
EP-4331558-A1 BIOCOMPATIBLE MELT-DENTIN SINGLE COMPONENT ADHESIVES Ivoclar Vivadent AG (LI) 2024-03-06 EP claimed
EP-3747948-B1 POLYURETHANE RESIN COMPOSITION KCC CORP (KR) 2024-01-03 EP claimed
EP-3368593-B1 IMPROVED BINDER COMPOSITIONS AND USES THEREOF KNAUF INSULATION SPRL (BE) 2023-12-06 EP claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
EP-3802625-B1 PHOTOPOLYMERIZED BIODEGRADABLE COPOLYMER FORMULATIONS FOR BIOMEDICAL APPLICATIONS UNIV DE COIMBRA (PT) 2022-04-20 EP claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
EP-3307800-B1 NOVEL POLYMER POLYOL COMPOSITIONS, A PROCESS FOR PREPARING THESE NOVEL POLYMER POLYOL COMPOSITIONS, FLEXIBLE FOAMS PREPARED FROM THESE NOVEL POLYMER POLYOLS AND A PROCESS FOR THE PREPARATION OF THESE FLEXIBLE FOAMS COVESTRO LLC (US) 2020-12-23 EP claimed
EP-0406161-B1 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA GEIGY AG (CH) 1995-02-22 EP claimed
EP-0361229-B1 Polymer-bonded dyes, process for their preparation and their use BAYER AG (DE) 1994-04-27 EP claimed
EP-0323120-B1 Photocurable ionomer cement systems MINNESOTA MINING & MFG (US) 1994-03-30 EP claimed
EP-0494842-A2 Rigid contact lenses with improved oxygen permeability CIBA-GEIGY AG (CH) 1992-07-15 EP claimed
EP-0207083-B1 COMPOSITIONS OF POLYCYCLOALKENYL-TERMINATED, UNSATURATED POLYESTERS OR POLYESTERAMIDES AND VINYL-REACTIVE PLASTICIZERS THEREFOR THE DOW CHEMICAL COMPANY (US) 1991-12-18 EP claimed
US-4777209-A IMPROVED DUCTILITY, ELONGATION AND TENSILE AND IMPACT STRENGTHS THE DOW CHEMICAL COMPANY (US) 1988-10-11 US claimed
EP-0207083-A4 COMPOSITIONS OF POLYCYCLOALKENYL-TERMINATED, UNSATURATED POLYESTERS OR POLYESTERAMIDES AND VINYL-REACTIVE PLASTICIZERS THEREFOR. DOW CHEMICAL CO (US) 1987-05-13 EP claimed
EP-0207083-A1 COMPOSITIONS OF POLYCYCLOALKENYL-TERMINATED, UNSATURATED POLYESTERS OR POLYESTERAMIDES AND VINYL-REACTIVE PLASTICIZERS THEREFOR. DOW CHEMICAL CO (US) 1987-01-07 EP claimed
WO-1986003757-A1 COMPOSITIONS OF POLYCYCLOALKENYL-TERMINATED, UNSATURATED POLYESTERS OR POLYESTERAMIDES AND VINYL-REACTIVE PLASTICIZERS THEREFOR THE DOW CHEMICAL COMPANY (US) 1986-07-03 WO claimed
EP-0030307-B1 COPOLYMER DISPERSIONS IN POLYFUNCTIONAL COMPOUNDS HAVING A PLURALITY OF ACTIVE HYDROGENS, METHOD OF MAKING THE COPOLYMER DISPERSIONS, AND A POLYURETHANE COMPOSITION PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1984-11-14 EP claimed