Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22589603 | 0.93 | TSHR (0.49) | RXFP1GAANPSR1TSHRHTT | |
| SCHEMBL28707693 | 0.89 | TSHR (0.46) | RXFP1GAANPSR1TSHRHTT | |
| SCHEMBL22589537 | 0.82 | KMT2A (0.45) | RXFP1GAANPSR1HTTMAPK1 | |
| SCHEMBL29363285 | 0.82 | KMT2A (0.45) | RXFP1GAANPSR1HTTMAPK1 | |
| SCHEMBL29365314 | 0.76 | TP53 (0.44) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL22589546 | 0.76 | TP53 (0.44) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL403348 | 0.75 | TSHR (0.66) | RXFP1GAANPSR1TSHRHTT | |
| SCHEMBL401916 | 0.75 | MAPK1 (0.65) | RXFP1GAANPSR1TSHRHTT | |
| SCHEMBL6314167 | 0.73 | HPGD (0.47) | RXFP1NPSR1TSHRMAPK1KMT2A | |
| SCHEMBL15191018 | 0.73 | HTT (0.49) | RXFP1GAANPSR1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020219729-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-10-29 | — | — | WO | disclosed |