SCHEMBL2260290

SCHEMBL2260290

N=C(S)Cn1cncn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4100563 0.78
SCHEMBL3763840 0.75 HDAC1 (0.41)
SCHEMBL7765796 0.74
SCHEMBL7467004 0.73
SCHEMBL10508172 0.73 EGLN3 (0.45)
SCHEMBL16402219 0.70
Bromide SCHEMBL6984871 0.70 EGLN3 (0.62)
SCHEMBL22234928 0.70
Hydrochloric Acid SCHEMBL1375589 0.70 EGLN3 (0.62)
SCHEMBL1178749 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338338-B2 Formulations comprising triazoles and alkoxylated amines JANSSEN PHARMACEUTICA N.V. (BE) 2012-12-25 US disclosed
US-20110196006-A1 IMAZALIL COMPOSITIONS COMPRISING ALKOXYLATED AMINES BYLEMANS DANY LEOPOLD JOZEFIEN 2011-08-11 US disclosed
US-20100099724-A1 Formulations Comprising Triazoles and Alkoxylated Amines JANSSEN PHARMACEUTICA N.V. (BE) 2010-04-22 US disclosed
US-7662748-B2 Such as azaconazole, bromuconazole, and N,N',N'-tris(2-hydroxyethyl)-N-cocoalkyl-1,3-diamino-propane; kits; for protection of crops, plants, fruits, seeds, wood products, thatch, biodegradable material and textiles JANSSEN PHARMACEUTICA, N.V. (BE) 2010-02-16 US disclosed
US-20090093505-A1 Imazalil compositions comprising alkoxylated amines JANSSEN PHARMACEUTICA N.V. (BE) 2009-04-09 US disclosed
EP-1784076-A1 IMAZALIL COMPOSITIONS COMPRISING ALKOXYLATED AMINES JANSSEN PHARMACEUTICA N.V. (BE) 2007-05-16 EP disclosed
EP-1473996-B1 FORMULATIONS COMPRISING TRIAZOLES AND ALKOXYLATED AMINES JANSSEN PHARMACEUTICA NV (BE) 2006-04-26 EP disclosed
WO-2006021556-A1 IMAZALIL COMPOSITIONS COMPRISING ALKOXYLATED AMINES JANSSEN PHARMACEUTICA N.V. (BE) 2006-03-02 WO disclosed
US-20050080089-A1 Formulations comprising triazoles and alkoxylated amines AKZO NOBEL CHEMICALS BV (NL) 2005-04-14 US disclosed
EP-1473996-A1 FORMULATIONS COMPRISING TRIAZOLES AND ALKOXYLATED AMINES JANSSEN PHARMACEUTICA N.V. (BE) 2004-11-10 EP disclosed
WO-2003065807-A1 FORMULATIONS COMPRISING TRIAZOLES AND ALKOXYLATED AMINES JANSSEN PHARMACEUTICA N.V. (BE) 2003-08-14 WO disclosed
EP-1273233-A1 Preservative formulations comprising an oxathiazine and alkoxylated amines JANSSEN PHARMACEUTICA N.V. (BE) 2003-01-08 EP disclosed