SCHEMBL22604659

SCHEMBL22604659

CC(C)(C)c1cc(CCC(=O)OCO)cc(C(C)(C)C)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.57
KMT2A Q03164 5/20 0.54
MEN1 O00255 4/20 0.48
ALDH1A1 P00352 5/20 0.46
TSHR P16473 3/20 0.46
MAPK1 P28482 3/20 0.46
LMNA P02545 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
BLM P54132 2/20 0.46
ATM Q13315 2/20 0.46
HIF1A Q16665 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
GMNN O75496 1/20 0.46
GABBR2 O75899 1/20 0.46
TP53 P04637 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
NFKB1 P19838 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15339370 0.93 GAA (0.51) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL208761 0.90 GAA (0.60) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL858494 0.90 GAA (0.60) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL17584989 0.89 GAA (0.56) GAAKMT2AMEN1ALDH1A1TSHR
Ethane SCHEMBL9814026 0.89 GAA (0.59) GAAKMT2AMEN1ALDH1A1TSHR
Methane SCHEMBL5968168 0.89 GAA (0.59) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL887482 0.88 GAA (0.55) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL13302847 0.88 GAA (0.57) GAAKMT2AMEN1ALDH1A1TSHR
Ethylene SCHEMBL4038426 0.88 GAA (0.57) GAAKMT2AMEN1ALDH1A1TSHR
Ethylene SCHEMBL6909288 0.88 GAA (0.57) GAAKMT2AMEN1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200339727-A1 ANTIOXIDANT FOR LOW-DENSITY POLYURETHANE FOAM SHELL OIL COMPANY 2020-10-29 US disclosed