SCHEMBL22606830

SCHEMBL22606830

Nc1ccc(-c2cc(C(F)(F)F)c(-c3ccc(N)cc3OC(F)(F)F)cc2C(F)(F)F)c(OC(F)(F)F)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.58
TSHR P16473 2/20 0.58
GLA P06280 1/20 0.58
POLB P06746 1/20 0.58
TRPA1 O75762 1/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
KIF11 P52732 1/20 0.35
AR P10275 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
SRC P12931 1/20 0.34
HPGD P15428 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22607189 1.00 GAA (0.58) GAATSHRGLAPOLBTRPA1
SCHEMBL714264 0.89 TSHR (0.48) GAATSHRGLAPOLBALDH1A1
SCHEMBL22607198 0.86 GAA (0.69) GAATSHRGLAPOLBTRPA1
SCHEMBL22607085 0.85 TSHR (0.45) GAATSHRGLAPOLBTRPA1
SCHEMBL22606685 0.85 GAA (0.62) GAATSHRGLAPOLBTRPA1
SCHEMBL22606816 0.85 GAA (0.67) GAATSHRGLAPOLBTRPA1
SCHEMBL24032682 0.82 POLB (0.62) GAATSHRGLAPOLBTRPA1
SCHEMBL22606815 0.82 GAA (0.49) GAATSHRGLAPOLBTRPA1
SCHEMBL30320923 0.82 POLB (0.62) GAATSHRGLAPOLBTRPA1
SCHEMBL31315637 0.80 GAA (0.57) GAATSHRGLAPOLBTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220325045-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-10-13 US disclosed
WO-2020219411-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES DUPONT ELECTRONICS, INC. (US) 2020-10-29 WO disclosed