SCHEMBL226070

SCHEMBL226070

C=C(C)C(=O)OCc1ccc(-n2nc3ccccc3n2)c(O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.40
NPC1 O15118 7/20 0.40
RAB9A P51151 7/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 6/20 0.37
POLB P06746 4/20 0.37
MAPT P10636 7/20 0.35
HPGD P15428 5/20 0.35
TDP1 Q9NUW8 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
KMT2A Q03164 1/20 0.34
IGF2BP2 Q9Y6M1 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384029 0.91 NPC1 (0.49) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL109007 0.91 NPC1 (0.49) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL4446963 0.88 APP (0.39) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL21332516 0.88 RXFP1 (0.36) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL29370022 0.86 NPC1 (0.37) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL225569 0.86 NPC1 (0.37) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL29373449 0.85 NPC1 (0.36) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL226211 0.85 NPC1 (0.36) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL11376140 0.83 POLB (0.41) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL29382372 0.81 NPC1 (0.45) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 457 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396287-A1 POLYESTER COMPOSITION AND ELASTOMER COATED ARTICLE MADE THEREWITH Celanese International Corporation (US) 2024-07-10 EP disclosed
US-12024622-B2 Composition, thermoplastic resin composition using same, and molded article thereof ADEKA CORPORATION (JP) 2024-07-02 US disclosed
CN-118201998-A Polyester composition and elastomer coated article made therefrom 国际人造丝公司 2024-06-14 CN disclosed
US-11999838-B2 Resin additive composition, thermoplastic resin composition, and molded article thereof ADEKA CORPORATION (JP) 2024-06-04 US disclosed
CN-118103449-A Laser transparent composition and molded article made therefrom 国际人造丝公司 2024-05-28 CN disclosed
EP-4372042-A2 RESIN ADDITIVE COMPOSITION, THERMOPLASTIC RESIN COMPOSITION, AND MOLDED ARTICLE THEREOF Adeka Corporation (JP) 2024-05-22 EP disclosed
CN-118019791-A Thermoplastic polymer composition with enhanced tracking resistance and polymer articles made therefrom 国际人造丝公司 2024-05-10 CN disclosed
EP-3424993-B1 RESIN ADDITIVE COMPOSITION, THERMOPLASTIC RESIN COMPOSITION, AND MOLDED ARTICLE THEREOF ADEKA CORP (JP) 2024-05-01 EP disclosed
EP-4357405-A1 NUCLEATING AGENT COMPOSITION, RESIN COMPOSITION, MOLDED ARTICLE THEREOF, AND METHOD FOR MANUFACTURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2024-04-24 EP disclosed
EP-4352150-A1 THERMOPLASTIC POLYMER COMPOSITION WITH INCREASED ELECTRICAL TRACKING RESISTANCE AND POLYMER ARTICLES MADE THEREFROM Celanese International Corporation (US) 2024-04-17 EP disclosed
EP-1384749-A1 ULTRAVIOLET ABSORBER FOR SYNTHETIC RESIN AND SYNTHETIC RESIN COMPOSITION CONTAINING THE SAME Asahi Denka Kogyo K. K. (JP) 2004-01-28 EP disclosed
EP-1375582-A2 Nucleating agent and crystalline polymer composition containing the same Asahi Denka Co., Ltd. (JP) 2004-01-02 EP disclosed
US-20030236329-A1 Nucleating agent and crystalline polymer composition containing the same ASAHI DENKA CO., LTD. (JP) 2003-12-25 US disclosed
US-20030162870-A1 Flame-retardant resin composition ASAHI DENKA CO., LTD. (JP) 2003-08-28 US disclosed
US-20030125432-A1 Granular composite additive for polyolefin, process for producing the same, and polyolefin composition containing the same ADEKA CORPORATION (JP) 2003-07-03 US disclosed
EP-1304350-A1 Flame-retardant resin composition Asahi Denka Co., Ltd. (JP) 2003-04-23 EP disclosed
CN-1394223-A Granular composite additive for polyolefin, process for producing the same, and polyolefin composition containing the same ASAHI DENKA KOGYO KK (JP) 2003-01-29 CN disclosed
EP-1266932-A1 GRANULAR COMPOSITE ADDITIVE FOR POLYOLEFIN, PROCESS FOR PRODUCING THE SAME, AND POLYOLEFIN COMPOSITION CONTAINING THE SAME ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2002-12-18 EP disclosed
US-6432875-B1 LOW MOLECULAR WEIGHT POLYESTER ASAHI DENKA KOGYO K.K. (JP) 2002-08-13 US disclosed
EP-0987122-A1 THERMAL RECORDING MATERIAL ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2000-03-22 EP disclosed