SCHEMBL22607802

SCHEMBL22607802

C/C(=C\CCCCCCCCCCCCCCCCO)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.45
TBXAS1 P24557 1/20 0.40
GPR84 Q9NQS5 1/20 0.39
FFAR1 O14842 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
CD81 P60033 1/20 0.37
FNTA P49354 1/20 0.35
FNTB P49356 1/20 0.35
SQLE Q14534 1/20 0.34
PPARG P37231 7/20 0.34
PPARA Q07869 2/20 0.34
TRPA1 O75762 1/20 0.34
FBP1 P09467 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8677618 1.00 EP300 (0.45) EP300TBXAS1GPR84FFAR1FFAR4
SCHEMBL743708 1.00 EP300 (0.45) EP300TBXAS1GPR84FFAR1FFAR4
SCHEMBL3679830 1.00 EP300 (0.45) EP300TBXAS1GPR84FFAR1FFAR4
SCHEMBL21065587 1.00 EP300 (0.45) EP300TBXAS1GPR84FFAR1FFAR4
SCHEMBL1686031 1.00 EP300 (0.45) EP300TBXAS1GPR84FFAR1FFAR4
SCHEMBL157091 1.00 EP300 (0.45) EP300TBXAS1GPR84FFAR1FFAR4
SCHEMBL9069525 1.00 EP300 (0.45) EP300TBXAS1GPR84FFAR1FFAR4
SCHEMBL22607803 1.00 EP300 (0.45) EP300TBXAS1GPR84FFAR1FFAR4
SCHEMBL21065579 1.00 EP300 (0.45) EP300TBXAS1GPR84FFAR1FFAR4
SCHEMBL454672 1.00 EP300 (0.45) EP300TBXAS1GPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3583092-B1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2021-05-26 EP claimed
EP-3583102-B1 HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2020-11-04 EP claimed