⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26126962 | 0.85 | — | — | |
| SCHEMBL28546243 | 0.85 | — | — | |
| SCHEMBL28229763 | 0.77 | — | — | |
| SCHEMBL14834291 | 0.74 | — | — | |
| SCHEMBL14063889 | 0.73 | — | — | |
| SCHEMBL15373551 | 0.73 | — | — | |
| SCHEMBL29116337 | 0.73 | — | — | |
| SCHEMBL28102742 | 0.73 | — | — | |
| SCHEMBL23038325 | 0.71 | SGPL1 (0.33) | — | |
| SCHEMBL16180731 | 0.71 | SGPL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731869-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |