Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071095 | 0.97 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1ALMNA | |
| SCHEMBL21071107 | 0.97 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1ALMNA | |
| SCHEMBL21070953 | 0.97 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1ALMNA | |
| SCHEMBL22609374 | 0.97 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1ALMNA | |
| SCHEMBL21071364 | 0.97 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1ALMNA | |
| SCHEMBL21070675 | 0.97 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1ALMNA | |
| SCHEMBL21070300 | 0.95 | IDO1 (0.43) | IDO1AKT1CTSSCTSLCTSB | |
| SCHEMBL21070267 | 0.95 | IDO1 (0.49) | IDO1AKT1ADRB2HTR1ALMNA | |
| SCHEMBL21069213 | 0.91 | IDO1 (0.43) | IDO1AKT1TLR2TLR1SIGMAR1 | |
| SCHEMBL21070834 | 0.89 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731869-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |