SCHEMBL22609753

SCHEMBL22609753

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nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
PGD P52209 1/20 0.30
HTT P42858 1/20 0.30
CYP2C9 P11712 1/20 0.30
PDE4A P27815 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27364734 0.95 TSHR (0.56) TSHRPGDHTTCYP2C9PDE4A
Ammonia Solution, Strong SCHEMBL11116924 0.92 TSHR (0.53) TSHRPGDHTTCYP2C9PDE4A
SCHEMBL27623112 0.92 TSHR (0.53) TSHRPGDHTTCYP2C9PDE4A
SCHEMBL7992773 0.90 TSHR (0.56) TSHRPGDHTTCYP2C9PDE4A
SCHEMBL9439905 0.90 TSHR (0.56) TSHRPGDHTTCYP2C9PDE4A
SCHEMBL1580351 0.90 TSHR (0.56) TSHRPGDHTTCYP2C9PDE4A
Water SCHEMBL28238706 0.87 TSHR (0.53) TSHRPGDHTTCYP2C9PDE4A
SCHEMBL14742965 0.87 TSHR (0.59) TSHRPGDHTTCYP2C9PDE4A
SCHEMBL27476046 0.85 TSHR (0.50) TSHRPGDHTTCYP2C9PDE4A
SCHEMBL1397720 0.84 TSHR (0.62) TSHRPGDHTTCYP2C9PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3963010-A1 SURFACE-TREATED MAGNESIUM OR CALCIUM ION-CONTAINING MATERIALS AS WHITE PIGMENTS IN ORAL CARE COMPOSITIONS Omya International AG (CH) 2022-03-09 EP disclosed
EP-3882315-A1 SURFACE-TREATED MAGNESIUM ION-CONTAINING MATERIALS AS WHITE PIGMENTS IN ORAL CARE COMPOSITIONS Omya International AG (CH) 2021-09-22 EP disclosed
WO-2020224957-A1 SURFACE-TREATED MAGNESIUM OR CALCIUM ION-CONTAINING MATERIALS AS WHITE PIGMENTS IN ORAL CARE COMPOSITIONS OMYA INTERNATIONAL AG (CH) 2020-11-12 WO disclosed
EP-3733786-A1 SURFACE-TREATED MAGNESIUM ION-CONTAINING MATERIALS AS WHITE PIGMENTS IN ORAL CARE COMPOSITIONS Omya International AG (CH) 2020-11-04 EP disclosed