Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.55 |
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.44 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22513590 | 0.90 | RECQL (0.54) | RECQLESR2ESR1RAB9AMAPK1 | |
| SCHEMBL13085156 | 0.87 | RECQL (0.71) | RECQLESR2ESR1RAB9AMAPK1 | |
| SCHEMBL26343666 | 0.87 | RECQL (0.51) | RECQLESR2ESR1RAB9AMAPK1 | |
| SCHEMBL22522326 | 0.87 | RECQL (0.59) | RECQLESR2ESR1RAB9AMAPK1 | |
| SCHEMBL22618152 | 0.86 | ESR1 (0.68) | RECQLESR2ESR1MAPK1HTT | |
| SCHEMBL22414159 | 0.86 | ESR1 (0.68) | RECQLESR2ESR1MAPK1HTT | |
| SCHEMBL12854005 | 0.86 | RECQL (0.69) | RECQLESR2ESR1RAB9AMAPK1 | |
| SCHEMBL3473850 | 0.86 | RECQL (0.69) | RECQLESR2ESR1RAB9AMAPK1 | |
| SCHEMBL22522328 | 0.85 | RECQL (0.52) | RECQLESR2ESR1RAB9AMAPK1 | |
| SCHEMBL22618150 | 0.85 | ESR1 (0.61) | RECQLESR2ESR1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10825994-B2 | Organic light emitting device and preparation method thereof | Wuhan China Star Optoelectronics Technology, Ltd. (CN) | 2020-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10825994-B2 | Organic light emitting device and preparation method thereof | CYBA, CYP1A2, CYP2B6 | RECQL 412/4885ESR2 646/4885ESR1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.