Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASK | O14936 | 2/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16377978 | 0.83 | KMT2A (0.34) | CASKCSNK1ETYRO3ACKR3 | |
| SCHEMBL16377724 | 0.79 | RAD52 (0.33) | ACKR3 | |
| SCHEMBL22626670 | 0.77 | NR1H4 (0.32) | — | |
| SCHEMBL22626337 | 0.76 | SLC8A1 (0.30) | — | |
| SCHEMBL22626523 | 0.76 | NR1H4 (0.34) | — | |
| SCHEMBL22626611 | 0.75 | RAD52 (0.32) | ACKR3 | |
| SCHEMBL22626444 | 0.73 | PLAT (0.31) | — | |
| SCHEMBL16377981 | 0.71 | — | — | |
| SCHEMBL16377938 | 0.70 | RAD52 (0.35) | ACKR3 | |
| SCHEMBL22626280 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |