Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22626523 | 0.84 | NR1H4 (0.34) | — | |
| SCHEMBL16377731 | 0.78 | CCNA2 (0.39) | TP53POLBCCNA2CDK2CCNA1 | |
| SCHEMBL16339912 | 0.77 | CCNA2 (0.42) | TP53POLBCCNA2CDK2CCNA1 | |
| SCHEMBL16340134 | 0.76 | CCNA2 (0.37) | TP53POLBCCNA2CDK2CCNA1 | |
| SCHEMBL22626315 | 0.71 | — | — | |
| SCHEMBL22626670 | 0.71 | NR1H4 (0.32) | — | |
| SCHEMBL22626596 | 0.70 | — | — | |
| SCHEMBL22626337 | 0.69 | SLC8A1 (0.30) | — | |
| SCHEMBL22626529 | 0.68 | HTR2A (0.31) | — | |
| SCHEMBL22626591 | 0.66 | CCNA2 (0.34) | CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |