Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 16/20 | 0.40 |
| ▸ | CDK2 | P24941 | 16/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 16/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22626591 | 0.93 | CCNA2 (0.34) | CCNA2CDK2CCNA1 | |
| SCHEMBL16333609 | 0.92 | CCNA2 (0.39) | CCNA2CDK2CCNA1F10 | |
| SCHEMBL22626261 | 0.90 | CCNA2 (0.32) | CCNA2CDK2CCNA1 | |
| SCHEMBL16339912 | 0.89 | CCNA2 (0.42) | CCNA2CDK2CCNA1F10 | |
| SCHEMBL17783213 | 0.88 | CCNA2 (0.37) | CCNA2CDK2CCNA1 | |
| SCHEMBL20580158 | 0.88 | PIK3CD (0.37) | — | |
| SCHEMBL16377780 | 0.87 | PIK3CD (0.45) | — | |
| SCHEMBL16377688 | 0.87 | PDE7A (0.30) | — | |
| SCHEMBL16377982 | 0.86 | RAD52 (0.37) | CCNA2CDK2CCNA1 | |
| SCHEMBL16377775 | 0.86 | RAD52 (0.36) | CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |