Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17789738 | 1.00 | KMT2A (0.31) | KMT2ATTKHTR3ATRPV1MAPT | |
| SCHEMBL17789695 | 1.00 | KMT2A (0.31) | KMT2ATTKHTR3ATRPV1MAPT | |
| SCHEMBL16377787 | 0.95 | MAPT (0.31) | TTKHTR3AMAPT | |
| SCHEMBL17789696 | 0.90 | KMT2A (0.32) | KMT2ATTKTRPV1MAPT | |
| SCHEMBL17789739 | 0.90 | KMT2A (0.32) | KMT2ATTKTRPV1MAPT | |
| SCHEMBL16377996 | 0.89 | CCNA2 (0.32) | TTKHTR3ATRPV1MAPT | |
| SCHEMBL17789730 | 0.89 | FGFR3 (0.33) | KMT2ATTK | |
| SCHEMBL22626500 | 0.86 | NTRK1 (0.30) | KMT2AMAPT | |
| SCHEMBL19326993 | 0.86 | MAPT (0.34) | MAPT | |
| SCHEMBL22626677 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |