Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22629455 | 0.88 | KDM1A (0.40) | KDM1AHDAC8HDAC6MAOBMAOA | |
| SCHEMBL22629304 | 0.87 | KDM1A (0.45) | KDM1AHDAC8HDAC6MAOBMAOA | |
| SCHEMBL22629375 | 0.87 | KDM1A (0.45) | KDM1AHDAC8HDAC6MAOBMAOA | |
| SCHEMBL22629277 | 0.87 | KDM1A (0.45) | KDM1AHDAC8HDAC6MAOBMAOA | |
| SCHEMBL21635960 | 0.87 | KDM1A (0.45) | KDM1AHDAC8HDAC6MAOBMAOA | |
| SCHEMBL22629154 | 0.87 | KDM1A (0.45) | KDM1AHDAC8HDAC6MAOBMAOA | |
| SCHEMBL22629608 | 0.87 | KDM1A (0.41) | KDM1AHDAC8HDAC6MAOBMAOA | |
| SCHEMBL22630414 | 0.86 | KDM1A (0.45) | KDM1AHDAC8HDAC6MAOBMAOA | |
| SCHEMBL22629208 | 0.84 | KDM1A (0.43) | KDM1AHDAC8HDAC6MAOBMAOA | |
| SCHEMBL22629108 | 0.84 | KDM1A (0.46) | KDM1AHDAC8HDAC6MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200345700-A1 | LSD1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200345700-A1 | LSD1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | KDM1B, KDM1A, KDM2A | KDM1A 2/4885HDAC8 88/4885HDAC6 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.