SCHEMBL2263207

SCHEMBL2263207

CC1(C)C2CC[C@@]1(C)C(C(=O)Cl)C2

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.44
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL924280 1.00 EPHX2 (0.44) EPHX2MAPTMAPK1KMT2AALDH1A1
SCHEMBL6043241 1.00 EPHX2 (0.44) EPHX2MAPTMAPK1KMT2AALDH1A1
SCHEMBL31180746 1.00 EPHX2 (0.44) EPHX2MAPTMAPK1KMT2AALDH1A1
SCHEMBL7158785 1.00 EPHX2 (0.44) EPHX2MAPTMAPK1KMT2AALDH1A1
SCHEMBL31180745 0.84 EPHX2 (0.44) EPHX2MAPTMAPK1KMT2AALDH1A1
SCHEMBL29710695 0.84 EPHX2 (0.44) EPHX2MAPTMAPK1KMT2AALDH1A1
SCHEMBL16678151 0.84 EPHX2 (0.44) EPHX2MAPTMAPK1KMT2AALDH1A1
SCHEMBL223632 0.84 EPHX2 (0.44) EPHX2MAPTMAPK1KMT2AALDH1A1
SCHEMBL6831561 0.84 EPHX2 (0.44) EPHX2MAPTMAPK1KMT2AALDH1A1
SCHEMBL7080802 0.84 EPHX2 (0.44) EPHX2MAPTMAPK1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110687235-B Method for analyzing nicotine isomer in fresh tobacco leaves 贵州省烟草科学研究院 2023-01-31 CN claimed
CN-109470789-B Chiral analysis method for nornicotine, anabasine and anatabine in tobacco and tobacco products 贵州省烟草科学研究院 2021-08-20 CN claimed
CN-110687235-A Derivatization and back-extraction method for removing interference of primary amine and secondary amine in tertiary amine chiral chromatographic analysis 贵州省烟草科学研究院 2020-01-14 CN claimed
CN-110658288-A Method for analyzing nicotine isomer in fresh tobacco based on derivatization purification and back extraction enrichment technology 贵州省烟草科学研究院 2020-01-07 CN claimed
EP-4653425-A1 METHOD FOR RAPIDLY PROVIDING PYRIDAZINES FROM TETRAZINES AND CIS-DIENOPHILES Tetrakit Technologies ApS (DK) 2025-11-26 EP disclosed
EP-4520751-A1 METHOD FOR RAPID OXIDATION OF DIHYDROPYRIDAZINES TO PYRIDAZINES University of Copenhagen (DK) 2025-03-12 EP disclosed
WO-2023170164-A1 METHOD FOR PROVIDING A LABELED SINGLE ISOMERIC CHEMICAL ENTITY TARGETING VECTOR BASED ON THE USE OF A SYMMETRICAL DIENE UNIVERSITY OF COPENHAGEN (DK) 2023-09-14 WO disclosed
CN-110658288-B Method for analyzing nicotine isomer in fresh tobacco based on derivatization purification and back extraction enrichment technology 贵州省烟草科学研究院 2023-01-31 CN disclosed
CN-110658288-B Method for analyzing nicotine isomer in fresh tobacco based on derivatization purification and back extraction enrichment technology 贵州省烟草科学研究院 2023-01-31 CN disclosed
CN-110687235-B Method for analyzing nicotine isomer in fresh tobacco leaves 贵州省烟草科学研究院 2023-01-31 CN disclosed
CN-109470789-B Chiral analysis method for nornicotine, anabasine and anatabine in tobacco and tobacco products 贵州省烟草科学研究院 2021-08-20 CN disclosed
CN-109470789-B Chiral analysis method for nornicotine, anabasine and anatabine in tobacco and tobacco products 贵州省烟草科学研究院 2021-08-20 CN disclosed
EP-0512848-B1 Enzymatic resolution of alpha-tertiary carboxylic acid esters GENZYME CORP (US) 1999-07-21 EP disclosed
EP-0619734-B1 NEW PHARMACEUTICAL FORMULATIONS OF 5-(2-CHLORO-1-HYDROXYETHYL)-4-METHYLTHIAZOLE ASTRA AB (SE) 1998-03-18 EP disclosed
US-5710283-A Preparation of chiral pyrrolidinone derivatives ZENECA LIMITED (GB) 1998-01-20 US disclosed
US-5492830-A CONTACTING RACEMIC ESTER IN AQUEOUS MEDIUM WITH SERINE CARBOXYPEPTIDASE TO HYDROLYZE S-ENANTIOMER PREFERENTIALLY GENZYME CORPORATION (US) 1996-02-20 US disclosed
US-5457201-A Chiral resolution process MERCK & CO., INC. (US) 1995-10-10 US disclosed
US-5385921-A Treatment for neurodegeneration, alzheimer's disease, huntington's chorea; antihypoxic agents, antiischemic agents AKTIEBOLAGET ASTRA (SE) 1995-01-31 US disclosed
US-5202260-A Partial hydrolysis, separation GENZYME CORPORATION (US) 1993-04-13 US disclosed
EP-0512848-A2 Enzymatic resolution of alpha-tertiary carboxylic acid esters GENZYME CORPORATION (US) 1992-11-11 EP disclosed