Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 20/20 | 0.88 |
| ▸ | KCNK9 | Q9NPC2 | 20/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432651 | 1.00 | KCNK3 (0.88) | KCNK3KCNK9 | |
| SCHEMBL21826463 | 0.94 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL22001496 | 0.90 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL21826663 | 0.89 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL21826388 | 0.87 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL29432720 | 0.87 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL24208146 | 0.85 | KCNK3 (0.86) | KCNK3KCNK9 | |
| Bafrekalant SCHEMBL21826404 | 0.85 | KCNK3 (1.00) | KCNK3KCNK9 | |
| SCHEMBL24208162 | 0.85 | KCNK3 (0.84) | KCNK3KCNK9 | |
| SCHEMBL22636202 | 0.85 | KCNK3 (1.00) | KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225185-A1 | COMBINATION OF AN α2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS WITH A TASK1/3 CHANNEL BLOCKER FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-12 | — | — | WO | claimed |